CHROMagar™ KPC - 5000 ml

Description

Chromogenic medium for detection of gram-negative bacteria with a reduced susceptibility to most of the carbapenem agents.

The product is composed of a powder base (CHROMagar Orientation) and 1 supplement (CHROMagar KPC supplement).

MEDIUM PERFORMANCE:
1. Detection of Gram negative bacteria expressing a reduced susceptibility to antibiotics of the Carbapenem family.
2. Detection of NDM-1: this new resistance gene recently reported, has the ability of destroying carbapenems. Bacteria harbouring this resistance mechanism (a metallo-betalactmase) can easily be screened with CHROMagar™ KPC.
3. Species identification thanks to the CHROMagar™ Orientation base.
4. Time and workload savings: there is no need for a selective pre-enrichment medium. Direct plating of the sample is possible.
5. Requires only 18-24 hours of incubation.
6. Unique commercially available culture medium for the detection of bacteria having reduced suceptibility to carbapenems.
7. Flexibility: CHROMagar™ KPC supplement is supplied with a more than 18 months shelf-life. This allows for flexibility of use, whether in an epidemic situation with many patients to screen, or whether for random surveillance of cultures.

TYPICAL APPEARANCE OF MICROORGANISMS:
E. coli Carbapenemᴿ→ Dark pink to reddish
Klebsiella, Enterobacter, Citrobacter Carbapenemᴿ→ Metallic blue
Pseudomonas Carbapenemᴿ → Cream, translucent
Other bacteria → Usually inhibited

Carbapenems are the last resort in treating many serious gram-negative infections. However, production of these enzymes results in resistance to penicillins, cephalosporins (i.e., cefepime, ceftriaxone), carbapenems (i.e., meropenem, ertapenem), and aztreonam, thereby making these pathogens truly multidrug-resistant and making their treatment very challenging.

Also available in 25 L (KPRT3-25 = RT413-25 + Supplement KP103-25)